AME Keynote Lecture Series

AME Keynote Lecture Series is a training program featuring designed presentation and talks given by international Key Opinion Leaders via video-recording and dedicated to bringing the most practical clinical research skills and know-hows to our trainees and helping them to avoid any unnecessary mistake or error.

How to conduct a high-quality cross-national multicenter RCT research: example of EURTAC program (Rafael Rosell, Spain)

Rafael Rosell, MD, PhD
Director, Cancer Biology & Precision Medicine Program Catalan Institute of Oncology; Germans Trias i Pujol Health Sciences Institute and Hospital Badalona, Barcelona, Spain

Research interests:  translational medical oncology with particular emphasis on the field of non-small-cell lung cancer with EGFR mutations, personalized cancer treatments

Dr. Rafael Rosell is Director of the Cancer Biology and Precision Medicine Program at the Catalan Institute of Oncology, Hospital Germans Trias i Pujol (Badalona, Barcelona, Spain), Chief Scientific Officer, Chairman and Founder of Pangaea Biotech SL (Barcelona), Chief Medical Officer and President of the Dr Rosell Oncology Institute, Quirón Dexeus University Hospital (Barcelona) and Founder and President of the Molecular Oncology Research Foundation (Barcelona). He is Founder and Director of International Relations and Projects, Spanish Lung Cancer Group (SLCG) and a member of the Foundation Council and Steering Committee of the European Thoracic Oncology Platform (ETOP).

Dr. Rosell’s contributions to translational medical oncology, with particular emphasis on the field of non-small-cell lung cancer with EGFR mutations, have earned him international recognition: in 2013 he was recognized by The Lancet as the highest authority in lung cancer in Europe; he received the Raymond Bourgine Award from the International Congress on Anti-Cancer Treatment (ICACT) for contributions to cancer research in 2012; in 2011 he was honored by the European Society of Medical Oncology (ESMO) with the Hamilton Fairley Award for lifetime achievements in science and clinical/laboratory research, and in 2008 the Bonnie J. Addario Lung Cancer Foundation presented him with the “Asclepios” Award to pioneers in research. Dr Rosell has also been named Professor Honoris Causa by the University of Cordoba in Argentina, Eminent Clinical Scholar in Residence by the Winship Cancer Institute, Emory Univeristy School of Medicine, Georgia, USA, and awarded the Silver Caravel by the city of Bari, Italy in recognition of his work in lung cancer.

The innovative work of Dr. Rosell’s multidisciplinary team has long focused on the design and selection of personalized cancer treatments based on genetic analysis and characterization of each patient’s tumor in order to optimize outcomes to treatment. Investigations center on characterization of new genes involved in the development of cancer and resistance to targeted therapies. Among others, the group has performed groundbreaking analyses of EGFR, KRAS and ALK as well as RNA expression analysis of multiple genes such as BRCA1, AEG1 and RAP80, demonstrating significant improvements in response to targeted treatments. In the field of lung cancer in particular they have achieved special recognition for their investigations in neoadjuvant chemotherapy, demonstrating a survival benefit in locally advanced lung cancer, as well as in metastatic patients.

Dr. Rosell has authored over 600 articles published in peer-reviewed medical and scientific journals, and he has given more than 800 presentations at medical and scientific conferences around the world. He is Editor-in-Chief of Translational Lung Cancer Research, Associate Editor for Clinical Lung Cancer and is on the Editorial Board of several professional journals, including Annals of Oncology, Clinical Cancer Research and Future Oncology. He is past president of the Asociación Espanola de Investigación sobre el Cancer (ASEICA) and past editor of Revista de Oncología, the official publication of five Spanish oncology societies.

Dr. Rosell is a member of the International Association for the Study of Lung Cancer (IASLC) and was Scientific Chair of their 2005 World Conference on Lung Cancer. He is an active member of the Protocol Review Committee of the European Organization for Research and Treatment of Cancer (EORTC), and serves on the Scientific Program Sub-Committee (non-small-cell lung cancer, metastatic) for the annual congress of the European Medical Oncology Society (ESMO). He was Scientific Chair of the 1st & 2nd European Lung Cancer Congress jointly sponsored by IASLC and ESMO. He also participated in the ASCO Scientific Programs Committee from 2002 through 2004.

Writing a meta-analysis (Giuseppe Lippi, Italy)

Giuseppe Lippi, MD
Full Professor of Clinical Biochemistry, Section of Clinical Biochemistry, University of Verona, Verona, Italy

Giuseppe Lippi was born in Padova (Italy) on October 4th, 1967. He has taken the degree in Medicine in 1992 and the specialization in Clinical Biochemistry and Laboratory Medicine in 1996. He currently serves as Full Professor of Clinical Biochemistry and Molecular Biology at the University of Verona(Italy), Director Laboratory Service of the University Hospital of Verona (Italy) and President of the School of Medicine of Verona University.

He has published over 1900 articles in peer-reviewed journals, his total Impact Factor is over 8000 and the Hirsch Index (H-index) is 113. He has participated to more than 600 national and international congresses and has given more over 300 lectures to national and international meetings. In 2017 he has been appointed as Secretary of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and he currently chairs the Task Force on COVID-19 of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). He has been awarded with the 2014 Management Sciences and Patient Safety Division Award of the American Association for Clinical Chemistry (AACC) for outstanding contributions in the field of patient safety in the clinical laboratory/healthcare industry, and with the 2015 Outstanding Speaker Award by the AACC. He has also received research grants from the European Community and from Regional Heath Care Services. Giuseppe Lippi is Editor in Chief of “Annals of Translational Medicine” and “Journal of Laboratory and Precision Medicine” and also serves as Associate Editor of the journals “Clinical Chemistry and Laboratory Medicine”, “Seminars in Thrombosis and Hemostasis” and “Diagnosis”, is National Representative of the Italian Society of Clinical Biochemistry and Laboratory Medicine (SIBioC) and member of the European Federation of Laboratory Medicine (EFLM) Working Group on Preanalytical Variability (WG-PRE).

The main fields of research include COVID-19, analytical and clinical validation of phenotypic and molecular biomarkers, diagnostics of thrombotic and hemorrhagic disorders and relevant assay methods, pre-analytical variability.